Journal: Viruses

Article Title: Persistence of Anti-ZIKV-IgG over Time Is Not a Useful Congenital Infection Marker in Infants Born to ZIKV-Infected Mothers: The NATZIG Cohort

doi: 10.3390/v13040711

Figure Lengend Snippet: ( A ) A comparison of Anti-ZIKV-IgG levels from birth to 18 months of age in infants born to ZIKV-infected mothers according to the presence of typical CZS (Cohort one) or no potentially ZIKV-related signs (cohort two). ( B ) A forest plot showing IgG mean differences between Cohorts one and two from birth to 12 months of age and their respective 95% credible intervals.

Article Snippet: Serum samples obtained at birth or within 6 months of age were tested for anti-ZIKV-IgM antibodies (ZIKV Detect TM 2.0 IgM Capture ELISA, InBios International, Inc., Seattle, WA, USA) [ ], which was repeated at later time points when positive.

Techniques: Comparison, Infection

Journal: Viruses

Article Title: Persistence of Anti-ZIKV-IgG over Time Is Not a Useful Congenital Infection Marker in Infants Born to ZIKV-Infected Mothers: The NATZIG Cohort

doi: 10.3390/v13040711

Figure Lengend Snippet: ( A ) Time to undetectable anti-ZIKV-IgG in infants born to ZIKV-infected mothers according to the presence of typical Congenital Zika Syndrome (CZS) (Cohort one) or no potentially ZIKV-related signs (Cohort two). ( B ) Time to undetectable anti-ZIKV-IgG in infants with CZS according to the reactivity of the anti-ZIKV-IgM within 6 months of age.

Article Snippet: Serum samples obtained at birth or within 6 months of age were tested for anti-ZIKV-IgM antibodies (ZIKV Detect TM 2.0 IgM Capture ELISA, InBios International, Inc., Seattle, WA, USA) [ ], which was repeated at later time points when positive.

Techniques: Infection

Journal: eLife

Article Title: The CryoEM structure of the Saccharomyces cerevisiae ribosome maturation factor Rea1

doi: 10.7554/eLife.39163

Figure Lengend Snippet:

Article Snippet: Software, algorithm , PyMOL(TM) 2.0.6 Schrodinger LLC , https://pymol.org/edu/?q=educational/.

Techniques: Protease Inhibitor, Software

Journal: Pharmaceutics

Article Title: A Volumetric Absorptive Microsampling UPLC-MS/MS Method for Simultaneous Quantification of Tacrolimus, Mycophenolic Acid and Creatinine in Whole Blood of Renal Transplant Recipients

doi: 10.3390/pharmaceutics14122547

Figure Lengend Snippet: Schematic diagram of the research content. ( a ) the traditional mode of TDM and renal function monitoring in renal transplant recipients. They must go to the hospital regularly for venous blood sampling and wait hours to get their reports. It must be admitted that the visit to the hospital is time-, labor-, and cost-consuming. ( b ) It shows the desired remote monitoring mode if a VAMS device is applied. In this way, the recipients can conduct microsampling of fingertip blood at home, and then the VAMS filled with capillary blood will be dried, sealed, and mailed to the hospital for analysis. This mode will allow them to receive an electronic report at home and complete regular TDM and renal function monitoring. ( c ) We developed and established a new robust method for simultaneous monitoring of TDM and renal function using single-sample analysis to provide technical support. The research contents include method development, analytical performance, clinical validation (compare DBS and VAMS), and a questionnaire (SUS) to assess feasibility. Materials sourced from BioRender.com.

Article Snippet: VAMS samplers (Mitra TM , 20 μL microsampling device) were supplied by Neoteryx (Torrance, CA, USA).

Techniques: Sampling, Biomarker Discovery